In 2020 the virus caused high mortality rates at critical care facilities. As the science catches up to this novel virus, early clinical reports and anatomical findings show progressive hypoxemia as the main cause of deterioration in patients with COVID-19.
As hypoxemia progresses, “standard therapy cannot penetrate the diffusion barriers in the lungs because they are limited by ambient pressure.” (2)
Preliminary evidence is showing HBOT is not limited by these barriers and may improve these patients’ conditions, especially if intervention occurs at early stages.
Clinical studies support the following benefits of hyperbaric oxygen therapy for those with COVID-19. For links to the clinical studies scroll to the bottom of this post.
If we extrapolate these observations to the COVID-19 situation, an early intervention before the need for mechanical ventilation could be of extraordinary utility for saving lives. In this regard hyperbaric oxygen therapy (HBOT) that consists of exposure to 100% oxygen under increased atmospheric pressure up to 2.4 atm could be a great resource to improve the outcome from the infection when it is administered at early stages as soon as a reduction of arterial oxygen concentration is detected.
Long COVID Syndrome (Long COVID), Post Acute COVID-19 Syndrome (PACS) or Post COVID-19 Syndrome (PCS) is defined as 'signs and symptoms that develop during or following an infection consistent with COVID-19, continue for more than 12 weeks and are not explained by an alternative diagnosis'. 1 in 10 infected individuals may suffer persistent symptoms, and we are facing an emerging problem that will severely affect individuals, health care systems and society for years to come.
We explore hyperbaric oxygen administered in a randomized placebo-controlled clinical trial as a potential treatment for patients suffering from Long COVID.
The overall hypothesis to be evaluated is that hyperbaric oxygen (HBO2) alleviates symptoms associated with Long COVID.
The following study is currently in progress to review the benefit of hyperbaric oxygen therapy for people with Post-Covid-19 syndrome.
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