Stem Cells
Hyperbaric oxygen Ttherapy shown to improve stem cell regeneration.
The innate ability of stem cells to differentiate into other types of cells with specialized functions (blood, brain or tissue cells) replenishes and regenerates the body from the effects of aging and disease.
Hyperbaric oxygen therapy (HBOT) has been shown to significantly increase the concentration of circulating stem/progenitor cells within the peripheral circulation system. By increasing blood plasma oxygen levels, bone marrow-derived stem cells were shown to significantly proliferate and mobilize. The proposed mechanism of action was through a nitric oxide-dependent mechanism. This evidence plays a key role in regenerative medicine as the increased number of stem cells in the body have the ability provide enhanced and accelerated physiological repair.
Studies have demonstrated the following therapeutic benefits of hyperbaric oxygen therapy on stem cells.
ENHANCE STEM CELL ACTIVITY WITH HBOT – DOCUMENTED PHYSIOLOGICAL EFFECTS:
- Activates nitric oxide synthase type 3 (NOS-3)
- Proliferates and mobilizes bone marrow-derived stem cells
- Improves engraftment and differentiation of several progenitor cell types in organs such as the spleen, bone marrow, brain, peripheral nerve, pancreas, cartilage, and heart
- Increase in colony-forming cells
- Stimulation of stromal-derived growth factor
- Reduces high ROS levels
- Promotes endothelial growth factor-2 for angiogenesis
- Increases CD34 expression and pluripotent stem cells
ENHANCE HEALING FROM DISEASE/INJURY WITH HBOT – CLINICALLY DOCUMENTED AND SUPPORTED THROUGH RESEARCH CITATIONS:
- Accelerates growth and repair of damaged tissue
- Improves tissue regeneration and organ functionality
- Promotes neurogenesis
- Stimulates osteogenesis
- Ameliorates diabetic symptoms
- Enhances recovery from heart attack